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Biomonitoring
In the field of human biomonitoring (HBM), we offer a comprehensive range of LC-MS and GC-MS-based methods tailored for the precise quantitative determination of environmental chemicals and their specific metabolites in various biological matrices, including urine, serum, plasma and saliva. Our commitment to accuracy and precision is what sets us apart. Our methods are routinely used in biomonitoring campaigns, allowing us to comprehensively assess both occupational and non-occupational exposures to environmental chemicals. At the heart of our services is a commitment to improving understanding of how these substances interact with the human body, ultimately promoting a healthier and more sustainable future.
Tobacco Harm Reduction
With over four decades of experience, ABF is a globally leading expert in bioanalysis for biomarkers of exposure related to tobacco and new emerging nicotine products, trusted by clients worldwide. We have analyzed biological samples for hundreds of (non-)clinical studies, applying the largest set of fully validated bioanalytical methods in the field of tobacco harm reduction. Our methods are regularly applied in exposure and nicotine PK studies, supporting regulatory product submissions especially in the US under FDA CTP's PMTA and MRTPA. We continuously expand our portfolio by developing and validating bioanalytical methods for new biomarkers of exposure and biomarkers of potential harm, staying at the forefront of scientific advancements. At ABF, we are committed to help our clients responsibly launch new nicotine products in the marketplace. Choose ABF for reliable and cutting-edge bioanalysis services in the field of tobacco harm reduction.
Scientific Contribution
A correlation study applied to biomarkers of internal and effective dose for acrylonitrile and 4-aminobiphenyl in smokers
Biomarkers, Volume 19(4), doi: 10.3109/1354750X.2014.910271
Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods
CORESTA Congress 2014, Quebec, Canada
Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods
Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x
Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products
Drug Testing and Analysis DOI: 10.1002/dta.3372
Wastewater-Based Epidemiology (WBE): Potential Application for Assessing the Use of Conventional and New Generation Tobacco and Nicotine Products
Contributions to Tobacco & Nicotine Research
Analysis of 18 mercapturic acids in urine samples from the German Environmental Specimen Bank-tackling the data gap in the human biomonitoring of VOCs in Europe
Journal of Exposure Science & Environmental Epidemiology
Accurate verification of nicotine and tobacco product use or abstinence using a multi-biomarker approach
Journal of Environmental Exposure Assessment