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Matching services
Biomonitoring
In the field of human biomonitoring (HBM), we offer a comprehensive range of LC-MS and GC-MS-based methods tailored for the precise quantitative determination of environmental chemicals and their specific metabolites in various biological matrices, including urine, serum, plasma and saliva. Our commitment to accuracy and precision is what sets us apart. Our methods are routinely used in biomonitoring campaigns, allowing us to comprehensively assess both occupational and non-occupational exposures to environmental chemicals. At the heart of our services is a commitment to improving understanding of how these substances interact with the human body, ultimately promoting a healthier and more sustainable future.
Tobacco Harm Reduction
With over four decades of experience, ABF is a globally leading expert in bioanalysis for biomarkers of exposure related to tobacco and new emerging nicotine products, trusted by clients worldwide. We have analyzed biological samples for hundreds of (non-)clinical studies, applying the largest set of fully validated bioanalytical methods in the field of tobacco harm reduction. Our methods are regularly applied in exposure and nicotine PK studies, supporting regulatory product submissions especially in the US under FDA CTP's PMTA and MRTPA. We continuously expand our portfolio by developing and validating bioanalytical methods for new biomarkers of exposure and biomarkers of potential harm, staying at the forefront of scientific advancements. At ABF, we are committed to help our clients responsibly launch new nicotine products in the marketplace. Choose ABF for reliable and cutting-edge bioanalysis services in the field of tobacco harm reduction.
Scientific Contribution
Analysis of 18 Urinary Mercapturic Acids by two Multiplex-LC-MS/MS Methods
CORESTA Congress 2014, Quebec, Canada
Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods
Analytical and Bioanalytical Chemistry, Volume 407, doi: 10.1007/s00216-015-8719-x
Analysis of aldehydes, propylene oxide and glycidol in tobacco smoke and e-cigarette vapor and their respective urinary biomarkers
CORESTA SSPT 2019, Hamburg, Germany
Analytical methods for the determination of carbonyls in aerosol from e-vapor products and cigarette smoke and their urinary biomarkers of exposure
CORESTA Congress 2018, Kunming, China
Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid
Archives of Toxicology, doi:10.1007/s00204-021-03097-x
Biomarkers of exposure specific to e-vapor products based on stable-isotope labeled ingredients
SRNT 2018, Baltimore, USA
Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients – methods
CORESTA SSPT 2017, Kitzbühel, Austria
Biomarkers of exposure specific to e-vapor products based on stable-isotope labelled ingredients–results
CORESTA SSPT 2017, Kitzbühel, Austria
Comparison of urinary mercapturic acid excretions in users of various tobacco/nicotine products
Drug Testing and Analysis DOI: 10.1002/dta.3372
Novel biomarkers to characterize exposure to aldehydes from e-vapor products based on stable-isotope constituents
CORESTA Congress 2018, Kunming, China
Novel biomarkers to characterize the specific exposure to aldehydes or epoxides from e-vapor products based on stable-isotope labeled constituents
SRNT 2019, San Francisco, USA