We offer a large portfolio of ISO 17025 accredited methods in biomarker analysis and biomonitoring with more than 40 years of experience! We developed 70+ robust, highly sensitive assays to support your (pre)clinical and epidemiological studies in compliance with GLP, GCP. Our biomarker data were used to support numerous submissions to regulatory agencies.
ABF is an ISO 17025 accredited bioanalytical contract research laboratory with more than four decades of experience in method development, validation and application in the field of biomarkers and biomonitoring
Our service goes beyond sample analysis
We help customers to evaluate and interpret data
We offer a large portfolio of bioanalytical methods for exposure assessment and biomarker identification
Human biomonitoring (HBM) is the determination of pollutants or their metabolites in biological material (blood, urine, saliva, etc.). With the help of HBM, the exposure to environmental chemicals can be assessed to identify vulnerable populations or regional differences.
Tobacco Harm Reduction
Tobacco harm reduction is a public health strategy to lower the health risks to individuals and wider society associated with using tobacco products. Biomarkers specific for the exposure to tobacco and smoke are key endpoints for evaluating new emerging nicotine products with a potentially reduced risk.
Cannabis and cannabinoid products represent a fast growing market in therapeutics, medicine and are legalized for recreational use in more and more countries. Risk assessment by measuring suitable biomarkers of exposure is a powerful tool in the evaluation of these products.
The metabolome represents the entity of all ‘small’ molecules (<1500 Dalton) and is most predictive of an organism's phenotype. Comparisons of the metabolome of well defined groups of individuals allow the identification of biomarkers, which are responsible for group differences.
In the past three years alone, we have analysed more than 150,000 samples mostly from clinical and pre-clinical studies, serving various industries.
Accreditation & Quality Management
ABF holds an accreditation according to ISO17025:2018. All analytical methods are fully validated according to FDA Guidance for Industry - Bioanalytical Method Validation. ABF's laboratory procedures were established to comply with the principles of GLP and GCP. Our quality system and laboratory work is monitored by internal and external audits on a regular basis. External audits are performed by accreditation bodies like the German DAkkS as well as the Sponsor in study-related audits.
What's your need?
We are constantly establishing new bioanalytical methods according to our customers' needs. For any specific request please contact us directly.
Recent Publications & Conference Contributions
Time trend of the exposure to geraniol in 24-h urine samples derived from the German Environmental Specimen Bank from 2004 to 2018
Pluym N, Stoeckelhuber M, Weber T, Scherer G, Scherer M, Kolossa-Gehring M
International Journal of Hygiene and Environmental Health, Volume 239, doi.org/10.1016/j.ijheh.2021.113880
1,2-Propylene Glycol: A Biomarker of Exposure Specific to e-Cigarette Consumption